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Sample size tables for clinical studies / David Machin [and others].

Contributor(s): Material type: TextPublication details: Chichester, UK ; Hoboken, NJ : Wiley-Blackwell, 2009.Edition: 3rd edDescription: 1 online resource (viii, 256 pages) : illustrationsContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9781444300710
  • 1444300717
  • 9781444300727
  • 1444300725
Subject(s): Genre/Form: DDC classification:
  • 615.5072/4 22
Online resources:
Contents:
Basic design considerations -- Distributions and confidence intervals -- Comparing two independent groups for binary data -- Comparing two independent groups for ordered categorical data -- Comparing two independent groups for continuous data -- Cluster designs, repeated measures data and more than two groups -- Comparing paired groups for binary, ordered categorical and continuous outcomes -- Comparing survival curves -- Equivalence -- Confidence intervals -- Post-marketing surveillance -- The correlation coefficient -- Reference intervals and receiver operating curves -- Observer agreement studies -- Dose finding studies -- Phase II trials -- Sample size software (SSS).
Action note:
  • digitized 2011 HathiTrust Digital Library committed to preserve
Summary: This book provides statisticians and researchers with the statistical tools - equations, formulae and numerical tables - to design and plan clinical studies and carry out accurate, reliable and reproducible analysis of the data so obtained. There is no way around this as incorrect procedure in clinical studies means that the researcher's paper will not be accepted by a peer-reviewed journal. Planning and analyzing clinical studies is a very complicated business and this book provides indispensable factual information.
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Includes bibliographical references (pages 239-248) and indexes.

Basic design considerations -- Distributions and confidence intervals -- Comparing two independent groups for binary data -- Comparing two independent groups for ordered categorical data -- Comparing two independent groups for continuous data -- Cluster designs, repeated measures data and more than two groups -- Comparing paired groups for binary, ordered categorical and continuous outcomes -- Comparing survival curves -- Equivalence -- Confidence intervals -- Post-marketing surveillance -- The correlation coefficient -- Reference intervals and receiver operating curves -- Observer agreement studies -- Dose finding studies -- Phase II trials -- Sample size software (SSS).

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Print version record.

This book provides statisticians and researchers with the statistical tools - equations, formulae and numerical tables - to design and plan clinical studies and carry out accurate, reliable and reproducible analysis of the data so obtained. There is no way around this as incorrect procedure in clinical studies means that the researcher's paper will not be accepted by a peer-reviewed journal. Planning and analyzing clinical studies is a very complicated business and this book provides indispensable factual information.

Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2011. MiAaHDL

Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL

http://purl.oclc.org/DLF/benchrepro0212

digitized 2011 HathiTrust Digital Library committed to preserve pda MiAaHDL

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