1 Amine Receptors in CNS. I. Norepinephrine -- 1. Introduction -- 2. Localizing Norepinephrine-Containing Synapses -- 3. Effects of Norepinephrine on Central Neurons -- 4. Action of Norepinephrine on Defined Postsynaptic Neurons -- 5. The Noradrenergic Projection to Rat Hippocampal Pyramidal Cells and Other Brain Stem Areas -- 6. Cyclic 3?,5?-Adenosine Monophosphate as a Mediator of Norepinephrine Action in the Central Nervous System -- 7. Conclusions -- 8. References -- 2 Amine Receptors in CNS. II. Dopamine -- 1. Introduction -- 2. Localization and Function of Dopamine -- 3. Synthesis and Degradation of Striatal Dopamine -- 4. Stimulus-Evoked Release of Dopamine in Striatum -- 5. Dopamine Receptor Activation: Effects of Dopamine on Striatal Neurons -- 6. Pharmacological Characterization of Presumed Dopaminergic Neurons -- 7. Presynaptic vs. Postsynaptic Dopamine Receptors -- 8. Behavioral Studies -- 9. Structural Conformations -- 10. Dopamine Receptor: Adenylate Cyclase -- 11. Conclusion -- 12. References -- 3 Amine Receptors in CNS. III. 5-Hydroxytryptamine in Brain -- 1. Introduction -- 2. Experimental Studies on 5-HT Receptors -- 3. Conclusions -- 4. References -- 4 Acetylcholine Receptors in Vertebrate CNS -- 1. Introduction -- 2. In Vivo Effects of ACh and Agonists on CNS -- 3. In Vitro Effects of ACh and Agonists on CNS -- 4. Significance of ACh Receptors -- 5. Evidence for Central Cholinergic Neurotransmission and Its Functional Significance -- 6. References -- 5 Receptor Feedback and Dopamine Turnover in CNS -- 1. Introduction -- 2. Dopamine as a Transmitter Substance in CNS -- 3. T ransmitter Metabolism in Brain Dopamine Neurons -- 4. Effect of Dopamine Receptor Blocking Drugs on Transmitter Turnover -- 5. Effect of Dopamine Receptor Stimulating Drugs on Transmitter Turnover -- 6. RelationBetween Drug Effects on Dopamine Turnover Regulation in Vivo and Dopamine-Stimulated Adenylate Cyclase Activity in Vitro -- 7. Evidence for Receptor-Mediated Control of Brain Dopamine Turnover in Man -- 8. References -- 6 Basic Mechanisms and Local Feedback Control of Secretion of Adrenergic and Cholinergic Neurotransmitters -- 1. Introduction -- 2. Secretion of Adrenergic and Cholinergic Neurotransmitters -- 3. Local Feedback Control of Secretion of Adrenergic and Cholinergic Neurotransmitters -- 4. References -- 7 The Cholinergic Receptor Protein from Fish Electric Organ -- 1. Introduction -- 2. A Model for the Electrogenic Action of Acetylcholine -- 3. Anatomy of the Electric Organs and of the Electroplaques -- 4. The Electric Discharge and the Electrophysiology of the Electroplaques -- 5. Pharmacology of the Isolated Electroplaque from Electrophorus -- 6. Localization of the Cholinergic Receptor Site in Electrophorus Electroplaque -- 7. Subcellular Fractionation of the Electric Organ -- 8. Permeability Response of Isolated Microsacs to Cholinergic Agonists -- 9. Characterization of the Cholinergic Receptor Site on Excitable Microsacs -- 10. Solubilization and Purification of the Cholinergic Receptor Protein -- 11. Chemical Properties of the Purified Receptor Protein -- 12. Physical Properties of the Cholinergic Receptor Protein -- 13. Binding Properties of the Purified Protein -- 14. Immunological Characterization of the Cholinergic Receptor Protein from Electrophorus -- 15. Conformational Transitions of the Receptor Protein Associated with Its Physiological Function -- 16. Turnover Number of the Cholinergic Ionophore -- 17. Reconstruction of a Chemically Excitable Membrane -- 18. Conclusion -- 19. References.

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