Amide Bond Activation
Materialtyp:
ArtikelUtgivningsinformation: MDPI - Multidisciplinary Digital Publishing Institute 2019Beskrivning: 1 electronic resource (466 p.)Innehållstyp: - text
- computer
- online resource
- 9783039212033
- 9783039212040
- Mathematics and Science
- Chemistry
- C-H
- C-H functionalization
- C-N ? bond cleavage
- C-N activation
- C-S formation
- C–H acidity
- C–H bond cleavage
- C–N bond cleavage
- C–O activation
- DFT study
- DMAc
- DMF
- HERON reaction
- Michael acceptor
- N-(1-naphthyl)acetamide
- N-dimethylacetamide
- N-dimethylformamide
- N-heterocyclic carbene
- N-heterocyclic carbenes (NHCs)
- N–C activation
- Pd-catalysis
- Suzuki-Miyaura
- Winkler-Dunitz parameters
- [2+2+2] annulation
- activation
- acyl transfer
- acylative cross-coupling
- addition reaction
- additivity principle
- alkynes
- amidation
- amide
- amide C–N bond activation
- amide activation
- amide bond
- amide bond activation
- amide bond resonance
- amide bonds
- amide hydrolysis
- amide resonance
- amides
- amidicity
- amination
- amine
- amino acid transporters
- aminoacylation
- aminosulfonylation
- anomeric effect
- antibacterial screening
- antiviral activity
- aryl esters
- aryl thioamides
- arynes
- base-catalyed hydrolysis
- biofilm eradication
- bridged lactams
- bridged sultams
- carbanions
- carbonylation
- carbonylicity
- catalysis
- catalyst
- catalysts
- cis
- cross-coupling
- crown ether
- c
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The amide bond represents a privileged motif in chemistry. The recent years have witnessed an explosion of interest in the development of new chemical transformations of amides. These developments cover an impressive range of catalytic N–C bond activation in electrophilic, Lewis acid, radical, and nucleophilic reaction pathways, among other transformations. Equally relevant are structural and theoretical studies that provide the basis for chemoselective manipulation of amidic resonance. This monograph on amide bonds offers a broad survey of recent advances in activation of amides and addresses various approaches in the field.
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eng
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