DNA Replication Controls
Material type:
ArticlePublication details: MDPI - Multidisciplinary Digital Publishing Institute 2017Description: 1 electronic resource (X, 304 p.)Content type: - text
- computer
- online resource
- 9783038425687
- 9783038425694
Open Access Unrestricted online access star
The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a hallmark of cancers and aging-related disorders.
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eng
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