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Novel Viral Vectors for Gene Therapy 2023
Materialtyp:
ArtikelUtgivningsinformation: MDPI - Multidisciplinary Digital Publishing Institute 2024Beskrivning: 1 electronic resource (214 p.)Innehållstyp: - text
- computer
- online resource
- 9783725805297
- 9783725805303
- Computing and Information Technology
- Computer science
- -117 HPFH type
- AAV
- AAV8
- CD34+ hematopoietic stem cells
- DMA
- HPFH enhancers
- HbF
- Ras pathway
- SARS-CoV-2
- VLP
- adeno-associated virus
- adeno-associated virus (AAV)
- adenovirus
- adenovirus vector
- animal-origin-free culture media
- approved drugs
- bovine capsid
- brain tumour
- cancer
- chemotherapy
- chronic disease
- clinical trials
- cryo-TEM
- cytolysis
- disinfection
- gene therapy
- genetically modified organisms (GMOs)
- globin gene therapy
- innate immune
- lentivirus
- limiting dilution
- luciferase imaging
- nES GEMMA
- novel serotype
- oncolytic viral therapy
- oncolytic virus
- pluripotency
- porcine capsid
- preclinical models
- receptor
- reovirus
- replication-competent adenovirus
- reprogramming
- sickle cell disease
- spike protein
- stemness
- suspension tests
- thalassemia
- therapy
- transduction
- vaccine
- vaccines
- vector
- viral vector
- viral vectors
- virucidal activity
- virus inactivation
- γ-globin lentiviral vector
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Viral vectors are gene transfer tools assembled from the backbones of naturally occurring viruses. These replication-incompetent vehicles transfer assigned payloads into eukaryotic cells. Numerous viral vector systems that influence cells or tissues have been used to perform basic and preclinical research. Some virus-derived vectors found their way into clinical practice.
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eng
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