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Coronavirus disease 2019 (COVID-19) has undeniably led to the worst worldwide healthcare outbreak of the twenty-first century. Our understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 virus), the agent that causes COVID-19, has dramatically improved over the past several years. Currently, healthcare systems are facing another COVID-19 outbreak in the form of long COVID or post-COVID-19 syndrome—that is, the development and presence of long-lasting symptoms after an acute SARs-CoV-2 infection. To date, more than 100 potential long-lasting post-COVID symptoms have been attributed to SARS-COV-2. This Special Issue, which is entitled "Latest Research in Post-COVID (Long-COVID): Pathological and Treatment Studies of Sequelae and Complications" as part of the journal Biomedicines, focuses on potential gaps regarding the identification, timeframe, mechanisms, and treatment strategies associated with the management of this post-COVID-19 condition. The issue includes fourteen published papers covering the following topics: (1) treatment of this post-COVID-19 condition; (2) neonatal repercussions of SARS-CoV-2 infection; (3) risk factors of severe COVID-19; (3) phenotyping of post-COVID pain; and (5) other topics.

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