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The Special Issue Reprint encompassing peer-reviewed articles on glaucoma and neuroprotection is timely, as the constellation of eye diseases is ever-increasing as the world's population ages. The aim of the Special Issue was to capture some leading aspects of on-going research into pathophysiology, genetics and current and future therapeutic treatment options to mitigate the signs and symptoms of these potentially blinding disorders, especially open-angle and normotensive glaucoma that affect millions worldwide. I hope that this collection of original research and review articles will spur further interest in these elements in the academic arena and in the biopharmaceutical industries.

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