Emergence and Control of African Swine Fever
Materialtyp:
ArtikelUtgivningsinformation: MDPI - Multidisciplinary Digital Publishing Institute 2025Beskrivning: 1 electronic resource (280 p.)Innehållstyp: - text
- computer
- online resource
- 9783725840373
- 9783725840380
- Medicine
- Medicine: general issues
- Public health and preventive medicine
- Epidemiology and Medical statistics
- A137R
- ASF
- ASFV
- ASFV vaccine
- ASFV-G-Δ9GL
- ASFV-G-∆I177L
- African Swine Fever
- African swine fever
- African swine fever virus
- African swine fever virus (ASFV)
- B-cell epitope
- Dominican Republic
- Germany
- NF-κB signaling pathway
- RNA-seq
- SWOT analysis
- T-cell epitope
- Uganda
- Vaccine adjuvants
- acceptability
- antigenic epitope
- antiviral
- biosecurity
- boar semen
- central variable region
- chronization
- clinical signs
- clinics
- commercial qPCR kits
- comparison
- conjoint analysis
- control
- control and preventive measures
- control measures
- disease control
- disinfectant
- dosing study
- epidemiology
- feeding
- gene-deleted strain
- genotype
- glycerol monolaurate
- gross findings
- histopathology
- immunopathology
- inactivation
- inflammation
- innate immunity
- live-attenuated vaccines
- long-term clinical studies
- mitigation
- monoglyceride
- multiplex crystal digital PCR (multiplex cdPCR)
- multiplex real-time quantitative PCR (multiplex qPCR)
- natural infection
- nucleic acid extraction
- oral uptake
- orally experimental infection
- p11.5
- participatory epidemiology
- pathology
Open Access Unrestricted online access star
African swine fever (ASF) is a highly lethal and contagious viral disease found in domestic pigs, wild boars, and wild suids, and it has significant economic consequences. This disease is currently endemic in many parts of the world, but the lack of an effective commercial vaccine for prevention and control makes the threat of ASF spreading to ASF-free regions more prominent. Currently, the emergence of a new highly lethal genotype I and II recombinant African swine fever viruses disrupted the ability of available vaccine candidates against genotype II in order to protect pigs against ASF. The emergence of this recombinant virus is an example of the complex dynamics that involve the natural infectious cycle of this pathogen. Currently, more research studies are needed to improve the control of ASF. These collections of studies include the areas of control (vaccination, drugs, disinfectants, and immunology), epidemiology, pathogenesis, and diagnostics. The studies compiled in this Reprint contribute to improving the knowledge of several critical aspects of this complex disease. I encourage the scientific community of ASFV to review these published studies.
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eng
Freely available e-book